The most buzzworthy primetime shows of the fall

"Supergirl," premieres October 26, 8:30 p.m. ET, CBS: As the fall season starts, this late October entry perhaps represents the biggest gamble of all. Not only is "Glee" alum Melissa Benoist's portrayal of the classic superhero likely to be held under a microscope, but the expensive series will be up against shows like "The Voice" and another comic book-based series, "Gotham." Fans hope it can soar past the competition, succeeding on major network CBS, as others like it have on the CW. Click through for more of what the fall has in store.

The most buzzworthy primetime shows of the fall

"The Muppets," premieres September 22, 8 p.m., ABC: As much as a show starring some of the most popular characters of all time seems like a slam dunk, the Muppets have seen mixed results on the small screen over the years ("Muppets Tonight," anyone?)

The most buzzworthy primetime shows of the fall

"Scream Queens," premieres September 22, 8 p.m., Fox: Producer extraordinaireRyan Murphy returns to Fox, with a show that combines the youthfulness and biting dialogue of "Glee" with his other hit, "American Horror Story." Emma Roberts, Lea Michele and Jamie Lee Curtis star in the show about sorority girls threatened by a masked killer (even Ariana Grande pops up).

The most buzzworthy primetime shows of the fall

"Heroes Reborn," premieres September 24, 8 p.m., NBC: In some ways, this is NBC trying to start over with a show that had an enormously successful first season, but went quickly downhill. This sequel to the original series hopes to regain that early success.

The most buzzworthy primetime shows of the fall

"The Grinder," premieres September 29, 8:30 p.m., Fox: Rob Lowe and Fred Savage: What's not to like? This comedy brings us the unlikely story of a TV lawyer trying to become a real one.

The most buzzworthy primetime shows of the fall

"Angel from Hell," premieres November 5, 9:30 p.m., CBS: The reason this show has buzz: Jane Lynch. Another "Glee" alum returns to TV, this time as a woman who may or may not be an unorthodox angel sent to help another woman on earth. Or she could just be off her rocker.

The most buzzworthy primetime shows of the fall

"Quantico," premieres September 27, 10 p.m., ABC: The network hopes to have its own "Homeland" with this series about young FBI recruits who might have a terrorist amongst them.

The most buzzworthy primetime shows of the fall

"Limitless," premieres September 22, 10 p.m., CBS: The Bradley Cooper movie about a man who has amazing abilities after taking a pill gets spun off into a series (with a cameo by Cooper in the first episode).

The most buzzworthy primetime shows of the fall

"Crazy Ex-Girlfriend," premieres October 19, 8 p.m., The CW: YouTube star and comedy writer Rachel Bloom could be a star in the making with this musical comedy about a woman obsessed with her high school boyfriend, whom she runs into one day by chance.

The most buzzworthy primetime shows of the fall

"Minority Report," premieres September 21, 9 p.m., Fox: Another spinoff, this is a follow-up to the Steven Spielberg movie but takes place many years later after the "pre-cogs" have returned into society -- but one can still see crimes before they happen.

The most buzzworthy primetime shows of the fall

"Blindspot," premieres September 21, 10 p.m., NBC: This series with Jaimie Alexander ("Thor") could just as easily be a smash hit as a flop. A woman tattooed all over her body is found naked in a bag in the middle of Times Square. Each tattoo is a clue to a crime.

The most buzzworthy primetime shows of the fall

"Ash vs. Evil Dead," premieres October 31, 9 p.m., Starz: Ash is back, as fans of the "Evil Dead" movies get to see Bruce Campbell once again kick undead butt.

The most buzzworthy primetime shows of the fall

"Marvel's Jessica Jones," streams November 20, Netflix: Marvel's second series for Netflix stars Krysten Ritter ("Don't Trust the B---- in Apt. 23") in a serious role as a former superhero turned private investigator.

The most buzzworthy primetime shows of the fall

"Into the Badlands," premieres November 15, 10 p.m., AMC: AMC hopes to do for martial arts what it did for zombies in this new series.

The most buzzworthy primetime shows of the fall

"American Horror Story: Hotel," premieres October 7, 10 p.m., FX: Lady Gaga leads a new cast of disturbing characters in the fifth installment of "AHS."

The most buzzworthy primetime shows of the fall

"CSI," series finale, September 27, 9 p.m., CBS: The show that launched the procedural series genre comes to an end after 15 seasons with a two-hour TV movie.

The most buzzworthy primetime shows of the fall

"Empire," returns September 23, 9 p.m., Fox: The biggest success story of last season is back and Fox is putting a lot of their eggs in this particular basket for this season.

The most buzzworthy primetime shows of the fall

"The Walking Dead," returns October 11, 9 p.m. AMC: Season six of the epic zombie apocalypse series is here, and should continue to take a big bite out of the cable competition. As usual, the new season remains shrouded in mystery.

The most buzzworthy primetime shows of the fall

"The Flash," returns October 6, 8 p.m., The CW: The "Fastest Man Alive" gave the CW one of its biggest hits of all time, with plotlines and twists that came at us even faster. Producers promise to up the ante even further this year.

The most buzzworthy primetime shows of the fall

"Gotham," returns September 21, 8 p.m., Fox: A Batman show without anyone in a cape? Turns out it worked, thanks to deliciously villainous performances by Robin Lord Taylor and the (now departed) Jada Pinkett Smith. The Joker should feature prominently this season. "Things have digressed into chaos now, and it's a long bumpy road," actor Sean Pertwee (Alfred) told CNN. "We have to get to the bottom of the barrel before a phoenix like young Master Bruce rises." (And you have just enough time to catch up with the recently released Blu-Ray for season one.)

The most buzzworthy primetime shows of the fall

"Scandal," returns September 24, 9 p.m., ABC: Kerry Washington returns as the now iconic character Olivia Pope for a fifth season, and fans still can't get enough of it.

The most buzzworthy primetime shows of the fall

"The Mindy Project," streams new episodes every Tuesday, Hulu: As Netflix did for "Arrested Development" and Yahoo! did for "Community," this comedy has been saved by a streaming service. We've already seen some big changes in the fourth season premiere, now streaming.

The most buzzworthy primetime shows of the fall

"The Last Man on Earth," returns September 27, 9:30 p.m., Fox: One of the weirdest concepts of recent memory made this a sleeper hit for Fox in the spring. Will Forte and Kristen Schaal will continue to explore the lighter side of the end of the world.

The most buzzworthy primetime shows of the fall

"The Leftovers," returns October 4, 9 p.m., HBO: Hardcore fans are dying to see what happens in season 2 of this series, which takes place after a rapture-esque event.

The most buzzworthy primetime shows of the fall

"The Big Bang Theory," returns September 21, 8 p.m., CBS: Will Leonard and Penny really go through with the wedding in Vegas? Are Sheldon and Amy done for good? Now in its ninth season as the most popular comedy on TV, it still remains fresh.

The most buzzworthy primetime shows of the fall

"The Goldbergs," returns September 23, 8:30 p.m., ABC: This show grounded in 1980s nostagia really came into its own in the second season. If you grew up in the '80s, it really hits home, and the cast have amazing chemistry.

The most buzzworthy primetime shows of the fall

"iZombie," returns October 6, 9 p.m., The CW: Critics have raved about this show which puts a very new twist on the zombie formula, with a terrific performance by Rose McIver, who -- in between eating brains and solving crimes -- tries to live a semi-normal life.

The most buzzworthy primetime shows of the fall

"South Park," new season Wednesdays 10 p.m., Comedy Central: It's been a long time since we last saw Cartman and the gang, and they wasted no time in the recent season premiere, covering Tom Brady, Caitlyn Jenner and Jared Fogle among other things. If that's a hint of what to expect this season, we can be sure "South Park" will take no prisoners in its 19th(!) season.

The most buzzworthy primetime shows of the fall

The most buzzworthy primetime shows of the fall

"Fresh Off the Boat," returns September 22, 8:30 p.m., ABC: One of the surprise hits of last year was the first Asian family sitcom in decades (which gives way to "Dr. Ken" this season on the same network). The laughs should continue in this second season.